In their annual online list, the animal rights group also slammed singers Aretha Franklin - who they crowned Biggest Loser - Kylie Minogue and Marilyn Manson and actress Lindsay Lohan for wearing fur and leather.
PETA branded Eva Longoria Parker a "streetwalker" and Kate Moss a "super tramp" in their Worst Dressed List.
In their annual online list, the animal rights group also slammed singers Aretha Franklin - who they crowned Biggest Loser - Kylie Minogue and Marilyn Manson and actress Lindsay Lohan for wearing fur and leather.
Referring to 'Desperate Housewives' star Eva, PETA said: "Eva Longoria is short on compassion. In her trashy furs, she looks like the streetwalker of Wisteria Lane. Eva is one 'Desperate Housewife' in need of a quickie divorce - from her stylist."
Talking about British supermodel Kate Moss, PETA added: "Nothing completes the transition from supermodel to super tramp like a fur coat. If Kate could see clearly through those bleary eyes, maybe she would clear her closet of those furs."
Lindsay was branded a "mean girl" for wearing fox fur, while Aretha was told to have some "R-E-S-P-E-C-T for animals".
'2 Hearts' singer Kylie Minogue was blasted for her penchant for python-skin bags.
The campaign group said: "What does Kylie Minogue have in common with her python purse? They are both cold-blooded. Come on Kylie, it's not cool to clutch an accessory made by nailing snakes to a tree and skinning them alive."
Previous winners of the Worst Dressed title include Paris Hilton, Kimberly Stewart and Nicole Richie.
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